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SKU PP-ONC-PNC28-5MG
PNC-28 is a synthetic peptide closely related to PNC-27, combining the HDM-2 (MDM2)-binding domain of p53 with a membrane-translocating peptide sequence, studied for tumor-selective cell interactions. Supplied for laboratory and educational research only.
Preclinical studies suggest PNC-28 binds HDM-2 on susceptible tumor cell membranes, promoting membrane pore formation and disruption of cellular integrity, a mechanism researchers have distinguished from conventional agents that target intracellular DNA or cell division pathways.
Experimental oncology research, including studies of HDM-2-targeted signaling, p53 pathway biology, and tumor-selective membrane disruption in breast, pancreatic, glioblastoma, and melanoma research models. Evidence remains preclinical, with no approved therapeutic indication.
Summarized from published research literature for informational purposes. Not a recommendation for use, and not an indication that this product is approved or intended for human or veterinary use.
Store lyophilized powder at -20°C, protect from light, moisture, and heat
Refrigerate at 2-8°C for short-term use. For extended storage, aliquot and freeze at -80°C, avoid repeated freeze-thaw cycles
Included per batch
Independent HPLC testing
LC-MS, batch matched
Yes. Reputable batches ship with a lot-specific CoA covering HPLC purity, mass spectrometry identity confirmation, and peptide sequence verification.
This product is sold for laboratory and educational research use only. It is not intended for human or veterinary use, and is not a drug, food, or cosmetic under applicable law unless explicitly labeled as such. Statements on this page have not been evaluated by any regulatory authority.
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